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For small molecules, DMPK is crucial.
Pharmacokinetics, efficacy, drug-drug interactions and toxicity can all be driven by how a drug is metabolised and transported across membranes.
A rigorous understanding of DMPK parameters and IVIVE will streamline lead optimisation and candidate selection and guide the potential complexity of your IND/CTA roadmap to clinical development.
DMPK Services Ltd, provides expert DMPK and pre-clinical IND consultancy - including ADME, In vitro studies, IVIVE (Cl, exposure vs target, early Dose-2-Man prediction etc), DDI, MIST, DILI, early de-risking strategies and Discovery:
- Study design(s)
- Data/report review
- Cost builds
- Study monitoring
- Facility/SOP review
- choice of isotope
- position of labelling
- quantity required
- maximizing its use
CONTACT
Feel free to contact me without obligation using either my direct email or via the contact box in the menu.
Email: Guy.webber@dmpkservices.com
Or connect and message me on LinkedIn: https://www.linkedin.com/in/guywebber/
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