top of page
![](https://static.wixstatic.com/media/11062b_6a134fc09ea34833a17d295e295ab517f000.jpg/v1/fill/w_1920,h_1080,al_c,q_90,enc_avif,quality_auto/11062b_6a134fc09ea34833a17d295e295ab517f000.jpg)
Early DeRisking
What are some of the major issues small molecule drugs face for approval?
+ Some of the major risks for small molecule drug development are driven by one thing - the metabolism of the drug.
+ Understand the metabolism of your molecule early - and you can considerably de-risk from failure or development issues before major investment decisions are made.
![risk.png](https://static.wixstatic.com/media/4128b0_2299ba05745345b78f11c3d653d19945~mv2.png/v1/fill/w_600,h_346,al_c,q_85,usm_0.66_1.00_0.01,enc_avif,quality_auto/risk.png)
+ Running certain in vitro assays early to identify hidden red flags can help de-risk away from these metabolism-mediated liabilities and can significantly add value to your molecule:
![risk.jpg](https://static.wixstatic.com/media/4128b0_f0fbd24f95a840779585f6a538acb518~mv2.jpg/v1/fill/w_747,h_432,al_c,q_80,usm_0.66_1.00_0.01,enc_avif,quality_auto/risk.jpg)
Click HERE to learn more about early de-risking strategies in my white paper downloadable from my Resource page
![DERISK.png](https://static.wixstatic.com/media/4128b0_e45f8b040b98417699ff8606bf8c35e6~mv2.png/v1/fill/w_299,h_564,al_c,q_85,usm_0.66_1.00_0.01,enc_avif,quality_auto/DERISK.png)
bottom of page